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Paper Information

Journal:   JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)   3RD WEEK APRIL 2011 , Volume 29 , Number 127; Page(s) 95 To 101.
 
Paper: 

Efficacy Of Simethicone In Preparation Prior To Upper Gastrointestinal Endoscopy

 
 
Author(s):  Ahsan Majid*, Babaei Leila, Gholamrezaei Ali, Emami Mohammad Hassan
 
* MEDICAL STUDENTS RESEARCH COMMITTEE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES AND POURSINA HAKIM RESEARCH INSTITUTE, ISFAHAN, IRAN
 
Abstract: 
Background: The presence of foam/bubbles in stomach and duodenum is a common problem during esophagogastroduodenoscopy (EGD) that interferes with precise evaluation of the mucosa. We evaluated the effectiveness of simethicone in reducing foam/bubbles in stomach and duodenum, endoscopy duration, and patient satisfaction.Methods: This double-blind, randomized, placebo-controlled trial was conducted on candidates for elective EGD referring to Poursina Hakim Clinic, Isfahan (Iran). Participants received 40 mg chewable tablet of simethicone or placebo, with 30 ml water, 15-30 minutes before the EGD. Foam/bubbles during endoscopy were assessed and graded by a single endoscopist from 0 to 3 and the endoscopy duration was recorded. Patient’s satisfaction was scored from 0 to 10.Findings: During the study, 90 and 83 patients were entered into the simethicone and placebo groups, respectively. Degree of foam/bubbles was significantly less in simethicone compared to placebo group (P=0.002). No difference was found between the two groups in foam/bubbles of duodenum (P>0.05).Duration of endoscopy was, on average, one minute shorter in simethicone compared with placebo group (P<0.001). Patient’s satisfaction was similar between the two groups. No adverse effect was observed from simethicone.Conclusion: Simethicone before EGD significantly reduce the foam/bubbles in stomach and provide better visibility for evaluating the mucosa, and also decrease the duration of endoscopy. Accordingly, routine administration of simethicone for preparation before EGD is recommended.
 
Keyword(s): ENDOSCOPY, SIMETHICONE
 
 
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APA: Copy

AHSAN, M., & BABAEI, L., & GHOLAMREZAEI, A., & EMAMI, M. (2011). EFFICACY OF SIMETHICONE IN PREPARATION PRIOR TO UPPER GASTROINTESTINAL ENDOSCOPY. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 29(127), 95-101. https://www.sid.ir/en/journal/ViewPaper.aspx?id=206951



Vancouver: Copy

AHSAN MAJID, BABAEI LEILA, GHOLAMREZAEI ALI, EMAMI MOHAMMAD HASSAN. EFFICACY OF SIMETHICONE IN PREPARATION PRIOR TO UPPER GASTROINTESTINAL ENDOSCOPY. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S). 2011 [cited 2022January20];29(127):95-101. Available from: https://www.sid.ir/en/journal/ViewPaper.aspx?id=206951



IEEE: Copy

AHSAN, M., BABAEI, L., GHOLAMREZAEI, A., EMAMI, M., 2011. EFFICACY OF SIMETHICONE IN PREPARATION PRIOR TO UPPER GASTROINTESTINAL ENDOSCOPY. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), [online] 29(127), pp.95-101. Available: https://www.sid.ir/en/journal/ViewPaper.aspx?id=206951.



 
 
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