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Paper Information

Journal:   INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)   SPRING 2011 , Volume 9 , Number SUPPL 2; Page(s) 54 To 54.
 
Paper: 

EVALUATION OF THE CORRELATION BETWEEN FOLLICULAR FLUID ANTI-MULLERIAN HORMONE LEVELS AND FERTILIZATION, AND EMBRYO QUALITY IN ART CYCLES

 
 
Author(s):  AFLATOONIAN A., MASHAYEKHY M.*
 
* DEPARTMENT OF OBSTETRICS AND GYNECOLOGY, SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, YAZD, IRAN
 
Abstract: 
Introduction: To evaluate whether high level of fluid anti-mullerian hormone level is more likely related to success of fertilization and better embryo quality.
Materials and Methods: 62 women whose follicular fluid sample was obtained from a single follicle in each patient underwent IVF with GnRH-agonist long protocol. Based on oocyte fertilization, the patients were divided into fertilized group (n=42) and non-fertilized group (n=20). Follicular fluid antimullerian hormone levels were measured in both groups and the quality of embryos was determined in fertilized group.
Results: Median of follicular fluid anti-mullerian hormone level in fertilized group was higher than that in non-fertilized group (5.7ng/ml vs.2.7 ng/ml) and a statistically significant difference was observed between the two groups. There was a significant difference between FF AMH level and scores of embryos (p<0.001).
The medians level of FF AMH were 6.7 ng/ml in good quality embryos and 3.80 ng/ml in fair quality embryos.
Conclusion: Our results indicate that follicular fluid anti-mullerian hormone level has positive correlation with fertilization and embryo quality. Therefore, follicular fluid anti-mullerian hormone level can be considered as a marker of IVF outcome.
 
Keyword(s): ANTI-MULLERIAN HORMONE, FOLLICULAR FLUID, FERTILIZATION, EMBRYO QUALITY, IN-VITRO FERTILIZATION
 
References: 
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