A serious interconnection is shaping up between medicine on the one hand and humanities on the other, in they past two decades. Under the general heading of humanities, our medical sciences and practice face issues like medical ethics, medical and health sociology, Social history of medicine and the functions of arts and literature in medicine. We first take a look at the reason why art, culture and literature are in general connected to psychiatry? We use examples of literature and art in Iran and worldwide to search the answers to this question. Then we discuss the issue of creativity which is closely connected with psychiatry. Understanding the creative mind the relationship between creativity and illnesses, creativity in patients and how it can be used in treatments are also important. Among different schools that modern psychiatry is built upon them the psychoanalytical school and the thinking of its founder Zigmund Freud have a special importance; and this importance increases when we talk about literature and psychiatry. And we live in an era that all existing concept are under question. Modernism, realism, surrealism and all schools are considered not enough. Schools are created that no independent word could be found to name them and are named based on their temporal relationship with others. Schools like Post Modernism. And, this comes at a time that we talk about “Post Psychiatry”. What do all of these mean?