The present study was performed to find the effect of planting date, plant density and different level of N fertilizer on yield and yield components of spring safflower on Isfahan variety. It was done in the research field of Arak Islamic Azad University in 2008-2009. The experiment was performed in factorial split plot based on RCBD with 4 replications and 48 plot. Treatment were selected as two planting dates (10th of May and 10th of July) and different level of N (46, 92 and 138 kg/ha) and two plant densities (400000 and 800000 plant/ha) hence 800000 plant per hectare executed in double row planting. The result showed that the highest yield was related to 10th of May planting date with 92 kg/ha N fertilizer and plant density of 800000 per hectare by 3052 kg/ha. The lowest yield was related to 10th of July planting date with 92 kg/ha N fertilizer and 400000 plant density per hectare. The delayed planting has very much influence in decreasing yield of safflower. So, planting in 10th of May has direct effect on safflower yield rather than planting in 10 July.