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Paper Information

Journal:   KNOWLEDGE AND HEALTH   SUMMER 2010 , Volume 5 , Number SIXTH IRANIAN CONGRESS OF EPIDEMIOLOGY; Page(s) 0 To 0.
 
Paper: 

SEROEPIDEMIOLOGY OF INFECTION WITH HERPES SIMPLEX VIRUS TYPE 2 (HSV2) AMONG ASYMPTOMATIC STUDENTS ATTENDING ISLAMIC AZAD UNIVERSITY OF KAZEROUN, SOUTHWEST OF IRAN

 
 
Author(s):  TAYYEBI D., SHARIFI ESFANDIAR
 
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Abstract: 

Introduction: Herpes simplex virus (HSV) infections are among the most common infectious diseases in humans. The prevalence of herpes simplex viruse type 2 (HSV-2) varies widely across the world. (1) Herpes simplex virus type 2 (HSV-2) is the cause of most genital herpes and is almost always sexually transmitted. Most HSV-2 infections are consequently expected to occur after the onset of sexual activity.(3) Genital herpes is a cause of morbidity and increases the risk of HIV acquisition, due to disruption of mucosal membranes. Data on prevalence of herpes simplex virus type 2 (HSV-2) infections are limited in Asia. Our study focuses on seroepidemiology of HSV-2 infection in Islamic Azad University of Kazeroun asymptomatic healthy students.
Methods: In our descriptive study, the study group comprised 450 students with the average age of 22.2. At the beginning, demographic data were recorded by using a questionnaire. For serological studies 5 ml of blood sample was collected and the serum was isolated by centrifugation. Enzyme linked immunosorbent assay (ELISA) was used for determination of immunoglobulin G (IgG) antibody titer to the HSV-2. Finally the results were analyzed by statistical methods.
Results: Overall, HSV-2-IgG antibody was positive in 105 persons (23.3%) out of 450 subjects and they had a previous infection. We can find a significant difference in prevalence between men and women but didn’t find any significant relationship between students with different field of study and their residence (p>0.05).
Conclusions: The overall incidence of HSV-2 infection in this study was 23.3%. Certainly information on age- and gender-specific prevalence of HSV-2 infection is crucial to guide herpes control strategies and prevention of HSV-2 infection should target individuals before they become sexually active.(6)

 
Keyword(s): HSV-2, SEROPREVALENCE, ELISA, IRAN
 
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