Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)   OCTOBER 2010 , Volume 28 , Number 110; Page(s) 451 To 458.
 
Paper: 

OPIUM CONSUMPTION AND RISK OF LIVER FIBROSIS IN CHRONIC HEPATITIS B AND C

 
 
Author(s):  SHAVAKHI AHMAD, SADEGHI ALI REZA*, MINAKARI MAHMOUD
 
* DEPARTMENT OF GASTROENTEROLOGY, SCHOOL OF MEDICINE, ISFAHAN UNIVERSITY OF MEDICAL SCIENCES, ISFAHAN, IRAN
 
Abstract: 

Background: In patients with hepatitis B and C, environmental factors such as smoking and alcohol can cause liver fibrosis progression. But opium effects on liver fibrosis progression are not clear. This study was designed to assess the relationship of opium user and liver fibrosis progression.
Methods: In this case-control study, sixty patients in hepatitis B group and sixty patients in hepatitis C group underwent liver biopsy due to hepatitis treatment and the severity of injury based on HAI (histopathological activity index) was evaluated. In the control group, patients were smoker but in the case group patients were smoker and opium user. In this study, correlation between amount and time of consumption of opium with HAI was determined.
Findings: There was significant relationship between HAI and opium using in both hepatitis B and C. In Hepatitis B, significant relationship was seen between amount of consumption of opium and grade of liver but no significant relationship was between amount of consumption of opium and stage of liver; also, there was not significant relationship between time of consumption of opium with stage and grade of liver. In hepatitis C, significant relationship was determined between stage with amount and time of consumption of opium and no relationship was noted between grade with amount and time of consumption of opium.
Conclusion: Correlation of opium and liver fibrosis progression, particularly in hepatitis C, was determined.

 
Keyword(s): HEPATITIS B, HEPATITIS C, OPIUM, LIVER FIBROSIS
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 69
 
Latest on Blog
Enter SID Blog