Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   ACTA MEDICA IRANICA   2010 , Volume 48 , Number 2; Page(s) 96 To 100.
 
Paper: 

ADVERSE REACTIONS OF TRIVALENT INFLUENZA VACCINE IN HIV-INFECTED INDIVIDUALS

 
 
Author(s):  HAJI ABD ALBAGHI MAHBOUBEH, JAM S., SEYED ALI NAGHI S.A.*, JAFARI SIROUS, MORADMAND BADI B., SABZEVARI D.
 
* IRANIAN RESEARCH CENTER FOR HIV/AIDS, IMAM KHOMEINI HOSPITAL, KESHAVARZ BLVD., TEHRAN, IRAN
 
Abstract: 

In this study, we assessed the adverse reactions to influenza vaccination in HIV- infected individuals. From November 2006 to January 2007, a total of 203 HIV-infected persons were recruited. Demographic data were collected. Subjects were evaluated 48 h and 15 days after vaccination for symptoms and significant health events as possible side effects. Participants were instructed to measure their temperature in the morning and evening for 2 days post- mmunization and to assess injection site and systemic adverse reactions. 80.3% of the subjects were male. The mean age of the subjects was 36.9±7.9 years. Local and systemic reactions were reported by 61 (30%) and 62 (30.5%) persons, respectively. The most common adverse reactions to the influenza vaccine included skin redness (37 cases), induration (32 cases), and pain (55 cases) as local reactions, and fever (22 cases), myalgia (46 cases), headache (12 cases) and weakness (35 cases) as general reactions. 1.4 % of the subjects had fever over 38.5°C. There were significant associations between myalgia and flushing with CD4 counts (P<0.05). We found no relationship between adverse reactions and sex, history of smoking, allergy, alcohol, and drug usage, stage of HIV infection, anti-retroviral therapies, anti-TB medication and previous vaccination. We concluded that inactivated influenza vaccine administered in HIV-infected adults did not result in potential adverse events in this study population.

 
Keyword(s): INFLUENZA, HUMAN, VACCINATION, HIV
 
References: 
  • ندارد
 
  pdf-File tarjomyar Yearly Visit 61
 
Latest on Blog
Enter SID Blog