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Paper Information

Journal:   IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)   DECEMBER 2009 , Volume 3 , Number SUPPLEMENT 1 (12TH INTERNATIONAL CONGRESS OF NEPHROLOGY, DIALYSIS, AND TRANSPLANTATION); Page(s) 82 To 83.
 
Paper: 

EFFICACY OF HEMODIALYSIS IN END STAGE RENAL DISEASE PATIENTS AND ITS INFLUENCING FACTORS (POSTER PRESENTATIONS: P331)

 
 
Author(s):  RAEISI DEHKORDI S., MORADI M., KARIMI K., ZANGANEH J., HOSSEINI S., GHANBARI T., ZARGHAM BROUJENI S.
 
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Abstract: 

Introduction. Hemodialyisis is one of the factors which strongly affects morbidity and mortality in patients under regular hemodialysis. Kt/v seems to be the best predictor of hemodialysis adequacy, but there are many equations to estimate kt/v which shows different results. The aim of this study was to determine the hemodialysis adequacy in our center by 3 different formulas to compare their differences and evaluation of its correlation with the other variables like serum albumin, BMI, hemodialysis shift (morning versus afternoon), sex, age and initiation time of hemodialysis.
Methods. In a cross-sectional analytic study those ESRD patients between 19 to 84 years old who were at least 3 months on regular hemodialysis were included. Data about sex, age, hemodialysis period, number of dialysis per week, dialysis time, pre- dialysis serum albumin, pre and post dialysis BUN and weight, BMI and shift of hemodialysis were collected. Kt/v was estimated in 3 different ways by Daugirdas-II, Barth and Lowrie formulas. Kt/v
³ 1.2 and URR ³ 65% were considered adequate hemodialysis index. Data were analyzed by SPSS version 11, Chi-square and t-test.
Results. A total of 41 patients were enrolled. Mean age of the patients was 54.78
± 17.62. Of the patients, 53.7% were men. Frequency of hemodialysis adequacy (kt/v ³ 1.2) was 56.1% by Daugirdas-II, 36.6% by Lowrie and 73.2% by Barth formulas, respectively, which shows significant fluctuations (contingency coefficient =0.55, P < 0.01). Thirty-nine percent of the patients had URR ³ 65%; 80.5% had hemodialysis 3 times a week; 36.0% had low BMI. Hemodialysis mean time was 3.80 hours and 34.1% of the patients were in morning shift. There

was significant relationship between hypoalbuminemia (<3.5g/dl) and hemodialysis inadequacy (P = 0.009).
No relationship was found between age (P = 0.12), sex (P = 0.16), hemodialysis shift (P = 0.39), and BMI (P = 0.86) and hemodialysis adequacy.
Conclusion. Hemodialysis inadequacy is a frequent complication in hypoalbuminemic patients; correction of nutritional defect may help to improve the problem.
Fluctuations between kt/v using different equations show importance of an agreement to use a single method.

 
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