Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   IRANIAN JOURNAL OF PEDIATRICS   MARCH 2010 , Volume 20 , Number 1; Page(s) 101 To 106.
 
Paper: 

PREMATURE LOSS OF PERMANENT TEETH IN ALLGROVE (4A) SYNDROME IN TWO RELATED FAMILIES

 
 
Author(s):  RAZAVI ZAHRA*, TAGHDIRI M.M., EGHBALIAN FATEMEH, BAZAZI N.
 
* DEPARTMENT OF PEDIATRICS, HAMADAN UNIVERSITY OF MEDICAL SCIENCES, IR IRAN
 
Abstract: 

Background: Allgrove syndrome is a rare autosomal recessive condition characterized by adrenal insufficiency, achalasia, alacrima and occasionally autonomic disturbances. Mutations in the AAAS gene, on chromosome 12q13 have been implicated as a cause of this disorder.
Case Presentation: We present various manifestations of this syndrome in two related families each with two affected siblings in which several members had symptoms including reduced tear production, mild developmental delay, achalasia, neurological disturbances and also premature loss of permanent teeth in two of them.
Conclusion: The importance of this report is dental involvement (loss of permanent teeth) in Allgrove syndrome that has not been reported in literature.

 
Keyword(s): ACHALASIA, ADRENOCORTICAL INSUFFICIENCY, ALACRIMIA (ALLGROVE, TRIPLE-A) PROTEIN, HUMAN, AAAS PROTEIN, HUMAN, TEETH, ALLGROVE SYNDROME, TRIPLE A SYNDROME PROTEIN, HUMAN
 
References: 
  • ندارد
 
  Yearly Visit 84
 
Latest on Blog
Enter SID Blog