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Paper Information

Journal:   IRANIAN JOURNAL OF CLINICAL INFECTIOUS DISEASES   2006 , Volume 1 , Number 1; Page(s) 35 To 37.
 
Paper: 

EVALUATION OF TUBERCULIN SKIN TEST AND BOOSTER EFFECT IN HEMODIALYSIS PATIENTS

 
 
Author(s):  AALIMAGHAM M.*, AMINIAFSHAR S., GACHKAR L., SHARAFI K., FARAHBAKHSH M.
 
* INFECTIOUS DISEASES AND TROPICAL MEDICINE RESEARCH CENTER, SHAHEED BEHESHTI UNIVERSITY OF MEDICAL SCIENCES, TEHRAN, IRAN
 
Abstract: 

Background: Tuberculosis is an endemic disease in Iran which may occur more frequently among hemodialysis patients. We have evaluated tuberculin skin test (TST) in hemodialysis patients in a university hospital in 2003-2004.
Materials and methods: Sixty-seven hemodialyis patients were enrolled for tuberculin skin tests. Indurations were measured 48-72 hours after the injection and then on the 7th day. Those with indurations less than 5mm in TST1 were introduced for TST2.
Results: Of 67 patients, 18(26.9%) had indurations of less than 5mm in TST1 and were introduce for TST2 among whom 7 (39%) had an induration measured less than 5mm. Of 18 cases, 11 (61%) were revealed to have booster effect that represent a ratio of 16% of all studied hemodialysis patients in our study.
Conclusion: It seems that the second TST is a better indicator of infectivity in hemodialysis patients, especially for patients who require repeated or annual estimation for M. tuberculosis infection.

 
Keyword(s): HEMODIALYSIS, BOOSTER EFFECT, TUBERCULOSIS, TUBERCULIN SKIN TEST
 
References: 
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