Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   CELL JOURNAL (YAKHTEH)   FALL 2009 , Volume 11 , Number SUPPL. 1; Page(s) 57 To 57.
 
Paper: 

PREMATURE LH SURGE IN INTRAUTERINE INSEMINATION (IUI) CYCLES AND GNRH ANTAGONIST RULE

 
 
Author(s):  POURMATROUD E.*, GHAZIZADEH S.
 
* VALI-E-ASR REPRODUCTIVE HEALTH RESEARCH CENTER, TEHRAN, IRAN
 
Abstract: 

Objective: To assessment the usefulness of premature LH surge prevention in intrauterine insemination cycle by GnRH antagonist administration.
Materials and Methods: 60 patients with unexplained or mild male infertility or minimal to mild endometriosis were enrolled to this prospective randomized controlled trial. 20 patients in group A (with GnRH antagonist) and 40 patients in group B (without GnRH antagonist) In all of participants CC+HMG were used for ovarian stimulation and when at least one follicle with
³ 16 mm diameter was seen, LH surge checked by urinary LH kit; in patients with negative results, HMG was continued, but in group A 0.25 mg Ganirelix SQ was administrated for two days,then in both groups HCG was injected on the third day and IUI was done 36-40 hours later. Pregnancy was the primary outcome.
Results: Base line characters and clinical parameters were similar in both groups except
³ 18 mm follicles in group A (p value= 0.003). Pregnancy rate in both groups was not significantly different (10% in group A and 15% in group B).
Conclusion: At least in CC+HMG stimulated cycles for IUI, the occurrence of premature LH surge could be useful and GnRH antagonist administration could have an interventional mistiming rule.

 
Keyword(s): IUI, GNRH ANTAGONIST, URINARY LH KIT
 
References: 
  • ندارد
 
  Yearly Visit 51
 
Latest on Blog
Enter SID Blog