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Paper Information

Journal:   SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES JOURNAL   WINTER 2009 , Volume 10 , Number 4 (SUPPL 1 COMPLIMENTARY MEDICINE); Page(s) 19 To 24.
 
Paper: 

COMPARISON OF THE EFFECT OF CITRUS AURANTIUM AND DIAZEPAM ON PREOPERATIVE ANXIETY

 
 
Author(s):  SHABANIAN GH.R., POURIA MOFRAD E., AKHLAGHI MAHMOUD*
 
* ANESTHESIOLOGY DEPT., HAJAR HOSPITAL, PARASTAR ST. SHAHREKORD, IRAN
 
Abstract: 

Background and aim: Preoperative anxiety is a common problem in patients before surgery which can be dangerous if does not be managed well. To reduce preoperative anxiety, anesthesiologists prescribe some synthetic premedication drugs for their patients. It has been shown that herbal medicine can have anxiolytic and sedative effects. In this study we aimed to compare the effect of Citrus aurantium and diazepam on preoperative anxiety. Method: In this double blind randomized clinical trial study, we selected 60 patients, aged between 14-48 years who were scheduled for elective surgery. Patients were randomly divided in two equal groups (Groups A and B). Patients in group A received 100 cc Citrus aurantium and patients in group B received diazepam (a pill of 5mg in 100 cc water) 2 hours before surgury. Anxiety scores, blood pressure (BP) and pulse rate (PR) were evaluated in two groups directly before and also two hours after premedication. Data were analyzed using c2 and paired t-tests. Results: There was a significant reduction in preoperative anxiety after premedication with Citrus aurantium (from 24.23±10.18 to 21.53±11.45) or diazepam (from 27.68±8.11 to 24.68±7.94). This reduction was equal in two groups. No significant difference was shown in BP and PR between two groups before and after premedication. Conclusion: Our data suggest that Citrous aurantium can be used to reduce preoperative anxiety.

 
Keyword(s): CITRUS AURANTIUM, DIAZEPAM, PREOPERATIVE ANXIETY
 
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