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Paper Information

Journal:   IRANIAN JOURNAL OF CLINICAL INFECTIOUS DISEASES   2008 , Volume 3 , Number 1; Page(s) 19 To 23.
 
Paper: 

STUDY OF HUMAN PAPILLOMA VIRUS IN ANOGENITAL CONDYLOMAS BY PCR METHOD

 
 
Author(s):  NASIRI S.*, GHALAM KARPOUR F., SABERI A., VESAL P.
 
* DERMATOLOGY RESEARCH CENTER, SHOHADAYE TAJRISH HOSPITAL, TEHRAN, IRAN
 
Abstract: 

Background: Anogenital condyloma is a relatively prevalent disease diagnosed in about 1.3 million Americans, annually. This disease is seen in 1% of sexually active adults. Aimed to evaluate anogenital condylomas with respect to human papilloma virus by PCR Method, present study was conducted in Skin Research Center, Shaheed Beheshti University of Medical Sciences.
Materials and methods: This cross-sectional study was conducted on 32 patients suffering from anogenital condyloma confirmed by pathological examination. Biopsy samples obtained from anogenital lesions of this disease were examined by PCR Method for existence of human papilloma virus as well as determination of virus type.
Results: In 12 patients (37%), human papilloma virus was detected by PCR Method. In addition, there was no difference in distribution of patients with respect to affliction with human papilloma virus between high-risk and low-risk groups. There was no relationship between clinical manifestation and type of papilloma virus.
Conclusion: This study is recommended to be repeated with more samples under more controlled condition.

 
Keyword(s): ANOGENITAL CONDYLOMA, HUMAN PAPILLOMA VIRUS, POLYMERASE CHAIN REACTION
 
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