Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL   FALL 2008 , Volume 7 , Number 3 (58); Page(s) 412 To 420.
 
Paper: 

PREVALENCE OF HBEAG -NEGATIVE AND HBV DNA POSITIVE IN PATIENTS WITH CHRONIC HEPATITIS B IN KHUZESTAN PROVINCE

 
 
Author(s):  ASAREHZADEGAN M.A.*, SHAKERINEZHAD GH.A., NOUROUZIRAD R., AMINI AKRAM
 
* IMMUNOLOGY DEPARTMENT, FACULTY OF MEDICINE, AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES, AHVAZ
 
Abstract: 

Objective: Hepatitis B is an endemic serious disease in many parts of the world. A significant proportion of patients with chronic hepatitis B are infected with a variant form of the hepatitis B virus (HBV) which has a low or abolished hepatitis B e-antigen (HBeAg) production. The aim of this study was to determine the prevalence of HBeAg-negative chronic hepatitis B cases in Khuzestan province.
Subjects and Methods: One hundred and sixty-two patients (102 men and 60 women; mean age 31±11.16 years) with chronic hepatitis B infection (HBsAg+/HBV DNA+) in Khuzestan province were included. Their HBeAg status was assessed using enzyme immunoassay (ELISA).
Results: Of the 162 patients with HBsAg+/HBV DNA+, 99 (61.1%) were HBeAg negative and 63 (38.9%) were HBeAg positive. The mean age ±SD in the former group was 33.1 ±9.9 and in the latter group was 27.7±12.2 years (P<0.001). HBeAg status had close correlation with age. The results showed no significant correlation between ALT levels and HBeAg negativity.
Conclusion: The results of this study indicate that HBeAg negative chronic hepatitis B has a high prevalence in Khuzestan province.

 
Keyword(s): HBV DNA, CHRONIC HEPATITIS B, HBEAG NEGATIVE, KHUZESTAN
 
References: 
  • ندارد
 
  Persian Abstract Yearly Visit 55
 
Latest on Blog
Enter SID Blog