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Paper Information

Journal:   JOURNAL OF OPHTHALMIC AND VISION RESEARCH   2009 , Volume 4 , Number 1; Page(s) 5 To 7.
 
Paper: 

KERATOPLASTY: MOVING TO THE FRONT (EDITORIAL)

 
 
Author(s):  NASIRI N., JALILIAN A.R.
 
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Abstract: 

Penetrating keratoplasty (PKP) has a long track record of high success rates compared to other tissue and organ transplantations. Despite the immunologic privilege of the cornea, the issue of immunological rejection cannot be overlooked and endothelial rejection is observed in up to 20% of eyes undergoing PKP.1 Repeat keratoplasties after rejection are increasingly more prone to rejection and the potential for a clear cornea becomes progressively lower with subsequent PKPs. Prospective long-term graft survival studies have also revealed disappointing results with PKP, and it is now recognized that graft survival rates and endothelial cell counts continue to decrease for many years after PKP.

 
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