Click for new scientific resources and news about Corona[COVID-19]

Paper Information

Journal:   IRANIAN JOURNAL OF IMMUNOLOGY (IJI)   DECEMBER 2008 , Volume 5 , Number 4; Page(s) 217 To 221.
 
Paper: 

COMPARISON OF THE SALIVARY IMMUNOGLOBULIN CONCENTRATION LEVELS BETWEEN CHILDREN WITH EARLY CHILDHOOD CARIES AND CARIES-FREE CHILDREN

 
DOI: 

IJIv5i4A5

 
Author(s):  BAGHERIAN ALI*, JAFARZADEH ABD ELAH, REZAEIAN MOHSEN, AHMADI SHIMA, REZAYATI M.T
 
* DEPARTMENT OF PEDIATRIC DENTISTRY, DENTAL SCHOOL, RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES, RAFSANJAN, IRAN
 
Abstract: 

Background: Early Childhood Caries (ECC) is one of the most common chronic childhood diseases. In spite of the global decrease in dental caries in the past decades, ECC has become a significant problem in many developing countries and also in a few industrialized nations. Saliva as a host factor can play an important role in the process of dental caries.
Objective: The aim of this study was to compare sIgA and IgG as saliva components between ECC and caries-free groups.
Methods: In this cross-sectional study, samples of unstipulated saliva of 90 children (45 in ECC group & 45 in caries-free group) were taken with Scully method. Then the concentration levels of sIgA and IgG were measured with Enzyme Linked Immunosorbent Assay and Single Radial Immunodiffusion methods.
Results: Mean concentration levels of salivary sIgA and IgG were significantly higher among children with ECC (p<0.05). There was also a weak inverse correlation between sIgA level and DMFT index in ECC group but it was not statistically significant (p=0.056).
Conclusion: The high concentration of salivary immunoglobulin in children with ECC may be associated with an increased antigenic load, leading to high production of antibodies.

 
Keyword(s): DENTAL CARIES, IMMUNOGLOBULINS, SALIVA
 
References: 
 
  pdf-File tarjomyar Yearly Visit 138
 
Latest on Blog
Enter SID Blog