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Paper Information

Journal:   IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)   SPRING 2008 , Volume 7 , Number 2; Page(s) 131 To 134.
 
Paper: 

SENSITIVITY PATTERN OF BACTERIA ISOLATED FROM CONTACT LENS WEARERS IN THE FACULTY OF PHARMACY, KARACHI UNIVERSITY STUDENT POPULATION

 
 
Author(s):  RAHIM N., BANON H.*, NAGHVI B.
 
* PHARMACEUTICAL SCIENCES, FEDERAL URDU UNIVERSITY, KARACHI, PAKISTAN
 
Abstract: 

Contact lens wearers are at great risk of developing microbial keratitis because of incorrect usages and unhygienic maintenance of contact lenses. Therefore, the present study was planned to provide data that will be helpful in selecting the anti-microbial to cure microbial keratitis.
One hundred bacterial isolates from conjunctiva of contact lenses wearer were isolated, identified and subjected to in vitro antibiotic sensitivity. In vitro sensitivity testing was done by Kirby-Bauer disc diffusion method. Out of forty-one isolates of Staphylococcus epidermidis isolated in this study, 82.9% and 75.6% isolates were sensitive to amoxycillin and cephradine respectively, where as isolates sensitive to neomycin, ciprofloxacin and chloramphenicol were found to be 95%, 92.9% and 87.8%, respectively. Thirty-nine isolates of Pseudomonas aeruginosa showed sensitivity to amoxicillin (2.6%), cephradine (7.7%), neomycin (69.2%), ciprofloxacin (82%), imipenem (84.4%) and chloramphenicol (28.3%), respectively. Multiresistant strains of pathogenic, as well as opportunistic microorganisms were isolated during the study. The results show a need for continuous monitoring of bacterial resistance trends.

 
Keyword(s): MICROBIAL KERATITIS, ANTI MICROBIAL, STAPHYLOCOCCUS EPIDERMIDIS, PSEUDOMONAS AERUGINOSA
 
References: 
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