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Paper Information

Journal:   IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN)   AUGUST 2007 , Volume 1 , Number 4; Page(s) 19 To 24.
 
Paper: 

COMPARING ANTIOXIDANT CAPACITY AND VITAMIN C VALUES BETWEEN UMBILICAL CORD AND MATERNAL BLOOD PLASMA AND THOSE IN NEWBORNS WITH HYPOXIA

 
 
Author(s):  BAZM AMOUN H.*, EMDADI M., SHEYKH NASRIN, NASERI R.
 
* HAMADAN UNIVERSITY OF MEDICAL SCIENCES
 
Abstract: 

Objective: Oxygen intoxication plays an important role in the pathogenesis of some fetal diseases such as encephalopathy, ischemia& hypoxia. Antioxidants can reduce oxidative damage in newborns. The object of this research was measuring total value of antioxidant and vitamin C in blood sample of pregnant women before delivery, and also in umbilical cord blood of their newborn, and repeating these measurements 48 hours after birth in newborns with hypoxia and controlling group.

Materials & Methods: The sample included 32 healthy pregnant women presented for delivery & also their newborns. The total values of antioxidant & vitamin C in plasma were measured by staining methods.

Results: There was no statistical meaningful difference in total values of antioxidants & vitamin C in women's blood & their newborn's cord blood. Also total values of antioxidant & vitamin C meaningfully increased in newborns with hypoxia after 48 hours.
Conclusion: total valuesof antioxidant & vitamin C in blood plasma of newborn, increase in oxidative damage as a defense mechanism.

 
Keyword(s): ANTIOXIDANTS, ASCORBIC ACID, HYPOXIA, UMBILICAL CORD BLOOD
 
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